Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6109605 | Journal of Hepatology | 2009 | 10 Pages |
Abstract
Liver DC respond distinctly to LPS stimulation by secreting IL-27 which synergizes with silencing of bioactive IL-12 activity leading to profound T cell inhibition.
Keywords
fms-like tyrosine kinase 3 ligandLPSFlt3LTregTLR4NPCAPCTLRGM-CSFantigen-presenting cellsinterferonIFNinterleukinToll-like receptornonparenchymal cellDendritic cellsRegulatory T cellsgranulocyte-macrophage colony-stimulating factorlipopolysaccharideMHCmajor histocompatibility complexpolymerase chain reactionPCR
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Authors
Yun Chen, Guoping Jiang, Horng-Ren Yang, Xiaodong Gu, Lianfu Wang, Ching-Chuan Hsieh, Hong-Shiue Chou, John J. Fung, Shiguang Qian, Lina Lu,