Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6109913 | Journal of Hepatology | 2009 | 12 Pages |
Abstract
This in vivo study confirms several findings regarding CYP2E1 and alcohol previously found only in vitro. These results provide in vivo evidence that CYP2E1 overexpression aggravates hepatic injury, and suggest that expression of cytokeratins 8 and 18 can be considered as biomakers for the progression of alcoholic liver disease.
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Authors
Angelica Butura, Kerstin Nilsson, Kengathevy Morgan, Timothy R. Morgan, Samuel W. French, Inger Johansson, Ina Schuppe-Koistinen, Magnus Ingelman-Sundberg,