Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6110104 | Journal of Hepatology | 2009 | 9 Pages |
Abstract
Propionibacterium acnes treatment MyD88-dependently induced hepatic granuloma formation. Subsequent LPS TRIF-dependently activated caspase-1 via Nalp3 inflammasome and induced IL-18 release, eventually leading to the liver injury.
Keywords
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Authors
Michiko Imamura, Hiroko Tsutsui, Koubun Yasuda, Ryosuke Uchiyama, Shizue Yumikura-Futatsugi, Keiko Mitani, Shuhei Hayashi, Shizuo Akira, Shun-ichiro Taniguchi, Nico Van Rooijen, Jurg Tschopp, Tetsuya Yamamoto, Jiro Fujimoto, Kenji Nakanishi,