Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6110120 | Journal of Hepatology | 2009 | 9 Pages |
Abstract
These findings demonstrate that FXR agonists may be useful for the treatment of non-alcoholic steatohepatitis.
Keywords
6α-ethyl-chenodeoxycholic acidCYP8B1FXRVCAM-1HSCMKCBSEPTIMP-1PDK4MCDNAFLDMMP-2MCP-1ALTSHP6ECDCACYP7A1farnesoid X receptorASTAspartate aminotransferaseAlanine aminotransferaseapoapolipoproteinNon-alcoholic steatohepatitis (NASH)sterol 12α-hydroxylasenon-alcoholic fatty liver diseaseHepatic stellate cellsmall heterodimer partnermatrix metalloproteinase 2methionine- and choline-deficientTissue inhibitor of metalloproteinase 1vascular cell adhesion molecule-1Nash Monocyte chemotactic protein-1Bile salt export pumpPyruvate dehydrogenase kinasecholesterol 7α-hydroxylaseKeratinocyte-derived chemokine
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Authors
Songwen Zhang, Juan Wang, Qiangyuan Liu, Douglas C. Harnish,