| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6110188 | Journal of Hepatology | 2009 | 10 Pages |
Abstract
Our data indicate, in addition to pharmacological effect of ARBs on PPARγ activation, a key biological role for AT1R in the regulation of hepatic lipid metabolism.
Keywords
TBARSHSCARBAT1RMCDPPARapoBALTVLDLalanine aminotrasferaseFFAACSLNAFLDPBSacyl-CoA synthetaseDMSOSmall interfering RNAsiRNAASTAspartate aminotransferaseangiotensinangiotensin II type 1 receptorAngiotensin II type 1 receptor blockerApolipoprotein BNon-alcoholic steatohepatitisnonalcoholic steatohepatitisFree fatty acidAngNonalcoholic fatty liver diseasenon-alcoholic fatty liver diseasetriglycerideDimethyl sulfoxideHepatic stellate cellrenin-angiotensin systemPhosphate buffered salinevery low density lipoproteinLipid metabolismthiobarbituric acid-reactive substancesNash wild-typeperoxisome proliferator-activated receptorperoxisome proliferator-activated receptor α
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Authors
Yoshitaka Nabeshima, Susumu Tazuma, Keishi Kanno, Hideyuki Hyogo, Kazuaki Chayama,