Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6114240 | Transfusion and Apheresis Science | 2013 | 5 Pages |
Abstract
The patients' hemodynamic conditions of septic shock due to intra-abdominal infection were improved by the longer duration of direct hemoperfusion with a polymyxin B-immobilized fiber column (PMX), reducing plasma endotoxins measured by the novel endotoxin detection method, named endotoxin scattering photometry (ESP) method; however, turbidimetric method could not detect endotoxins. We also observed the reduction in the endotoxin after passing through column by ESP method even after the longer duration of PMX. ESP method may more sensitively detect endotoxins than the ordinary turbidimetric method. Moreover, we demonstrated the ability of endotoxin adsorption in spite of the longer duration of PMX.
Keywords
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Authors
Tomoharu Shimizu, Toru Obata, Hiromichi Sonoda, Hiroya Akabori, Takahisa Tabata, Yutaka Eguchi, Yoshihiro Endo, Tohru Tani,