Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6114276 | Transfusion and Apheresis Science | 2013 | 7 Pages |
Abstract
We examined the donor factors that may affect the yield of peripheral blood stem cell (PBSC) mobilized from healthy donors. Pre-apheresis PB-CD34+ cell count was the only factor that correlated with PBSC yield. Leukocyte count (LC) and monocyte count (MC) correlated with PB-CD34+ cell. Male gender and PB-CD34+ cell count of at least 87.1/μL and 69.8/μL on day-4 and -5 of G-CSF were associated with the ability to harvest at least 5 Ã 106/kg CD34+ cells after one apheresis. We concluded that gender and PB-CD34+ cell count are important predictors of PBSC yield. LC and MC may serve as surrogate markers for estimating the PB-CD34+ cell count.
Keywords
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Authors
S.A.W. Fadilah, M.I. Mohd-Razif, Z.A.Z. Seery, T. Nor-Rafeah, W.J. Wan-Fariza, A. Habsah, C.F. Leong,