| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6114453 | Autoimmunity Reviews | 2015 | 9 Pages |
Abstract
The purpose of this review is to summarize in SSc the most relevant vascular biomarkers and the main associations between vascular biomarkers and capillaroscopic parameters and/or the presence of digital ulcers. Vascular biomarkers could become useful predictive factors of vascular damage in SSc, allowing an earlier management of vascular complications.
Keywords
EndoglinsENGPBMCsENGAT1RNVCRBPPDGFCapillaroscopyECMTNF-like weak inducer of apoptosisETARvasculopathyTWEAKDCRPlGFVEGFRANGPTLsoluble vascular cell adhesion moleculesVCAManti-annexin V antibodiesTGF-βMmpsCCRPAHSSCdcSScangiopoietin-like proteinAECAECssICAMNailfold videocapillaroscopyAnti-endothelial cell antibodiessoluble endoglinangiopoietinAngiogenesissystemic sclerosisSystemic sclerosis (scleroderma)diffuse cutaneous systemic sclerosisendothelinAnginterleukintransforming growth factor-βDigital ulcersperipheral blood mononuclear cellsEndothelial cellsplacental growth factorVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)platelet-derived growth factorPulmonary arterial hypertensionExtracellular matrixMatrix metalloproteinasesJAMsjunctional adhesion moleculessoluble intercellular adhesion moleculeBiomarkersRaynaud's phenomenonretinol binding proteinchemokine receptorDecoy receptorVascular endothelial growth factor receptors
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Authors
Inês Chora, Serena Guiducci, Mirko Manetti, Eloisa Romano, Celestina Mazzotta, Silvia Bellando-Randone, Lidia Ibba-Manneschi, Marco Matucci-Cerinic, Raquel Soares,