| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6114645 | Autoimmunity Reviews | 2012 | 8 Pages |
Abstract
In this review, we first provide a general overview of ERAP1 and ERAP2 genes, their biological functions and their relevancy in autoimmunity. We then discuss the importance of GWAS and the case-control studies that confirm the relevancy of ERAP single-nucleotide polymorphism associations and their linkage with particular MHC class I haplotypes, supporting a putative functional role in the autoimmune process.
Keywords
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Immunology
Authors
Alessandra Fierabracci, Annamaria Milillo, Franco Locatelli, Doriana Fruci,