Article ID Journal Published Year Pages File Type
6115048 Current Opinion in Immunology 2014 6 Pages PDF
Abstract

- iNKT cells provide innate, cognate help for T-dependent type II antigens.
- iNKT cells provide adaptive, noncognate help for T-D type 1 and T-I antigens.
- Cognate antigen drives splenic iNKT cells to arrest in the MZ then help GC B cells.
- Nanoparticles containing glycolipids are highly efficient activators of iNKT cells.
- Glycolipid and antigen containing nanoparticles are promising vaccine candidates.
Related Topics
Life Sciences Immunology and Microbiology Immunology
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