Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6115048 | Current Opinion in Immunology | 2014 | 6 Pages |
Abstract
- iNKT cells provide innate, cognate help for T-dependent type II antigens.
- iNKT cells provide adaptive, noncognate help for T-D type 1 and T-I antigens.
- Cognate antigen drives splenic iNKT cells to arrest in the MZ then help GC B cells.
- Nanoparticles containing glycolipids are highly efficient activators of iNKT cells.
- Glycolipid and antigen containing nanoparticles are promising vaccine candidates.
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Authors
Emilie E Vomhof-DeKrey, Jennifer Yates, Elizabeth A Leadbetter,