Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6115149 | Current Opinion in Immunology | 2012 | 7 Pages |
Abstract
⺠Tolerance is required to commensal bacteria and depends on regulatory T cells. ⺠Regulatory T cells specific to commensal bacteria are generated from naïve T cells in the periphery. ⺠Bacterial products can facilitate Treg cell function via the induction of IL-10, an immunosuppressive cytokine. ⺠Specific commensal bacterial species induce inflammatory or tolerogenic T cell responses in the gut.
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Authors
Katherine M Nutsch, Chyi-Song Hsieh,