Article ID Journal Published Year Pages File Type
6115149 Current Opinion in Immunology 2012 7 Pages PDF
Abstract
► Tolerance is required to commensal bacteria and depends on regulatory T cells. ► Regulatory T cells specific to commensal bacteria are generated from naïve T cells in the periphery. ► Bacterial products can facilitate Treg cell function via the induction of IL-10, an immunosuppressive cytokine. ► Specific commensal bacterial species induce inflammatory or tolerogenic T cell responses in the gut.
Related Topics
Life Sciences Immunology and Microbiology Immunology
Authors
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