Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6115151 | Current Opinion in Immunology | 2012 | 7 Pages |
Abstract
⺠NLR proteins have been genetically associated with and studied in models of IBD. ⺠Mice deficient for specific NLRs are susceptible to bacterial and chemical colitis. ⺠NLR proteins are important mediators between the host and the resident microbiota. ⺠NLR proteins control innate cytokine responses and cellular proliferation.
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Authors
Stephen J Rubino, Thirumahal Selvanantham, Stephen E Girardin, Dana J Philpott,