Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6115160 | Current Opinion in Immunology | 2012 | 10 Pages |
Abstract
⺠Genetic defects predispose to fungal infections and illustrate key defense mechanisms. ⺠C-type lectin receptor signaling pathways play a central role in immunity to fungi. ⺠Toll-like receptor agonism can resolve fungal infections. ⺠IL-17 is a key mediator of antifungal immunity, particularly at mucosal surfaces. ⺠Experimental fungal vaccines elicit protective immunity by Th1 and Th17 cells.
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Authors
Salomé LeibundGut-Landmann, Marcel Wüthrich, Tobias M Hohl,