Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6115165 | Current Opinion in Immunology | 2012 | 6 Pages |
Abstract
⺠CD45RA re-expressing T cells are pre-senescent memory T cells. ⺠Although non-proliferative, these cells exert potent effector function. ⺠CD45RA re-expressing T cells reside in skin, BM and spleen but not lymph nodes. ⺠Cell generation is cytokine driven and antigen independent. ⺠CD45RA re-expressing cell cycle block is maintained by inhibitory signalling.
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Authors
Sian M Henson, Natalie E Riddell, Arne N Akbar,