Article ID Journal Published Year Pages File Type
6115165 Current Opinion in Immunology 2012 6 Pages PDF
Abstract
► CD45RA re-expressing T cells are pre-senescent memory T cells. ► Although non-proliferative, these cells exert potent effector function. ► CD45RA re-expressing T cells reside in skin, BM and spleen but not lymph nodes. ► Cell generation is cytokine driven and antigen independent. ► CD45RA re-expressing cell cycle block is maintained by inhibitory signalling.
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