Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6115167 | Current Opinion in Immunology | 2012 | 6 Pages |
Abstract
⺠Regulatory T cells (Treg) accumulate with age in mice and humans. ⺠The pro-apoptotic molecule Bim is progressively downregulated in Treg with aging. ⺠Treg accrual may negatively impact immune responsiveness in aged mice and humans.
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Authors
Jana Raynor, Celine S Lages, Hesham Shehata, David A Hildeman, Claire A Chougnet,