Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6115170 | Current Opinion in Immunology | 2012 | 7 Pages |
Abstract
⺠Latent VZV is maintained in sensory neurons because of VZV-specific T-cell immunity. ⺠This immunity declines with age - the number/function of early effectors and effector memory. ⺠The loss of this T-cell immunity correlates with the occurrence of herpes zoster. ⺠A herpes zoster vaccine can restore this immunity and prevent herpes zoster. ⺠Suggestions are offered to improve the efficacy of zoster vaccine.
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Authors
Myron J Levin,