| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6115213 | Current Opinion in Immunology | 2012 | 8 Pages |
Abstract
⺠Regulatory T cells play a prominent role in maintaining mucosal tolerance in the intestine. ⺠Both Foxp3+ Tregs and Tr1 cells contribute to mucosal tolerance through production of IL-10. ⺠Mucosal tolerance is differentially regulated in the small intestine and colon. ⺠IL-10â and Foxp3â associated immune defects lead to chronic intestinal disease.
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Authors
Sharon Veenbergen, Janneke N Samsom,