| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6115225 | Current Opinion in Immunology | 2012 | 5 Pages |
Abstract
⺠Gene-expression based predictors of response to vaccination have been developed and show promise in influenza and yellow-fever virus vaccines. ⺠Gene-expression based predictors often fail to provide mechanistic insight in the basis for vaccine response. ⺠New analytic and experimental tools now allow the function of individual genes in predictive signatures to be identified. ⺠Enriching predictive signatures with functional information about their constituent genes will make gene-expression based predictors more robust.
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Authors
W Nicholas Haining, Bali Pulendran,