| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6115247 | Current Opinion in Immunology | 2012 | 7 Pages |
Abstract
⺠i-proteasomes are a proteasome-isoform with different active sites and higher degradation capacity. ⺠ROS production by alternative NADPH-Oxidases is innate to many cell types. ⺠IFNs trigger ROS production and the formation of oxidant damaged DRiPs. ⺠i-proteasomes are required for improved antigen presentation in infected cells and protect cytokine challenged cells from oxidative stress.
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Authors
Elke Krüger, Peter-M Kloetzel,