Article ID Journal Published Year Pages File Type
6115248 Current Opinion in Immunology 2012 8 Pages PDF
Abstract
► Peptide splicing by the proteasome produces diverse MHC-I binding peptides. ► Two proteasome subtypes that are intermediate between standard and immunoproteasome. ► Cytosolic metallopeptidases produce antigenic peptides presented by MHC class I. ► Insulin-degrading enzyme, nardilysin and thimet oligopeptidase. ► Increased diversity of the antigenic peptide repertoire.
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Life Sciences Immunology and Microbiology Immunology
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