| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6115252 | Current Opinion in Immunology | 2012 | 7 Pages |
Abstract
⺠DM and MHCII molecules form stable complexes in the absence of peptide. ⺠Peptide binding induces dissociation of DM from MHCII. ⺠MHCII molecules with fully bound peptides do not interact with DM. ⺠Dissociation of the peptide N-terminus from the MHC groove is required for DM binding. ⺠Key principles of peptide loading are similar between MHC class I and II molecules.
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Authors
Monika-Sarah ED Schulze, Kai W Wucherpfennig,