| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6115262 | Current Opinion in Immunology | 2013 | 8 Pages |
Abstract
⺠ILC2 provide an innate source of type-2 cytokines (IL-5, IL-9 and IL-13). ⺠IL-13 production by ILC2 is critical to anti-helminthic immunity. ⺠ILC2 regulate allergic airways inflammation and lung tissue homeostasis. ⺠ILC2 development is instructed by the transcriptional regulators, RORα and Gata3. ⺠Bone marrow ILC2 precursors give rise to mature ILC2 upon adoptive transfer.
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Authors
Jennifer A Walker, Andrew NJ McKenzie,