Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6115266 | Current Opinion in Immunology | 2013 | 6 Pages |
Abstract
⺠NKT cells are inherently reactive to self-antigens presented by CD1d molecules. ⺠Self-antigens are made to mimic foreign antigens upon recognition by type-I NKT TCRs. ⺠There are multiple ways to trigger a type-I NKT response in vivo. ⺠Several different self-antigens can stimulate type-I NKT cells. ⺠The main mouse model for the study of type-I NKT cell autoreactivity is imperfect.
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Authors
Laurent Gapin, Dale I Godfrey, Jamie Rossjohn,