Article ID Journal Published Year Pages File Type
6115266 Current Opinion in Immunology 2013 6 Pages PDF
Abstract
► NKT cells are inherently reactive to self-antigens presented by CD1d molecules. ► Self-antigens are made to mimic foreign antigens upon recognition by type-I NKT TCRs. ► There are multiple ways to trigger a type-I NKT response in vivo. ► Several different self-antigens can stimulate type-I NKT cells. ► The main mouse model for the study of type-I NKT cell autoreactivity is imperfect.
Related Topics
Life Sciences Immunology and Microbiology Immunology
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