Article ID Journal Published Year Pages File Type
6115268 Current Opinion in Immunology 2013 7 Pages PDF
Abstract
► MAIT cells recognize riboflavin derivatives originating from bacteria. ► Selection by hematopoietic thymic cells induce MAIT cell-specific features. ► MAIT cells are effector tissue targeted T cells resistant to xenobiotics. ► MAITs secrete IFN-γ and IL-17 and display context-dependent effector activities. ► Human MAITs encompass most, if not all, IL-17 producing CD8 T cells.
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