| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6115273 | Current Opinion in Immunology | 2013 | 6 Pages |
Abstract
⺠Immune suppressive leukocytes are prominent in pancreatic cancer. ⺠T cell infiltration is rare throughout disease progression. ⺠Pancreatic tumors may therefore remain intrinsically sensitive to T cell killing. ⺠Blockade of tumor GM-CSF blocks myeloid inflammation and mediates T cell immunity. ⺠Combination immunotherapies in pancreatic cancer are warranted.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Robert H Vonderheide, Lauren J Bayne,