Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6115277 | Current Opinion in Immunology | 2013 | 8 Pages |
Abstract
⺠Lymphotoxin and LIGHT mediate inflammation in a range of human autoimmune diseases. ⺠The Lymphotoxin-LIGHT Network mediates cancer inflammation in hematologic and solid tumors. ⺠Frequent somatic mutations implicate HVEM as a universal tumor suppressor gene in lymphoma. ⺠Rewiring Lymphotoxin LIGHT Network can alter tissue microenvironments to promote tumor immunity.
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Authors
Ryan L Bjordahl, Christian Steidl, Randy D Gascoyne, Carl F Ware,