| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6115281 | Current Opinion in Immunology | 2013 | 13 Pages |
Abstract
⺠Cancers are often oncogene addicted. ⺠Oncogene addiction is mediated by tumor intrinsic and immune-dependent mechanisms. ⺠Tumor intrinsic mechanisms include proliferative arrest, apoptosis, and differentiation. ⺠Immune-dependent programs include CD4+ T cells and cytokines. ⺠Combining immune and targeted therapy may be a more effective cancer therapy.
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Authors
Stephanie C Casey, David I Bellovin, Dean W Felsher,