Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6115290 | Current Opinion in Immunology | 2013 | 6 Pages |
Abstract
⺠Cancer-targeted therapies are being tested to synergize with tumor immunotherapy. ⺠Epigenetic modulators increase tumor antigen expression. ⺠BRAF inhibitors have paradoxical activation effects on lymphocytes. ⺠BRAF inhibitors can decrease cancer-released immune suppressive factors. ⺠PI3K/AKT pathway inhibitors can directly activate T memory cells.
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Authors
Antoni Ribas, Jedd D Wolchok,