| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6115334 | Current Opinion in Immunology | 2012 | 8 Pages |
Abstract
⺠Type I IFN appears to be a central pathway dysregulated in SLE. ⺠Most SLE patients have a prominent IFN gene signature in blood. ⺠Over half of the common alleles associated with SLE map into the type I IFN pathway. ⺠Rare, monogenic SLE-like diseases also show activation of type I IFN.
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Authors
Paola G Bronson, Christina Chaivorapol, Ward Ortmann, Timothy W Behrens, Robert R Graham,