| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6115335 | Current Opinion in Immunology | 2012 | 6 Pages |
Abstract
⺠A large number of associations for autoimmunity have been identified, generally involving common variants of modest effect. ⺠Many associations defined by GWAS are in non-coding regions and appear to regulate quantitative effects on gene expression. ⺠A large fraction of the common variants act through quantitative changes in thresholds for immune signaling and activation.
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Authors
Peter K Gregersen, Betty Diamond, Robert M Plenge,