| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6115339 | Current Opinion in Immunology | 2012 | 7 Pages |
Abstract
⺠The contribution of mouse studies to understanding the genetics of human autoimmune diseases is reviewed. ⺠Classical inbred strains have limited genetic diversity, which limits the power of QTL studies. ⺠The possibilities for genetically engineering mice are (almost) without limits. ⺠Phenotypic differences between mice and humans are related to species, mouse strain and microbiota.
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Authors
Joerg Ermann, Laurie H Glimcher,