Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6116013 | Diagnostic Microbiology and Infectious Disease | 2013 | 4 Pages |
Abstract
The Check-MDR Carba test (Check-Points, Wageningen, Netherlands), which is based on specific molecular recognition of blaNDM, blaKPC, blaOXA-48, blaVIM, and blaIMP genes by DNA probe ligation and real-time PCR detection, was evaluated on 183 well-characterized Gram-negative rods. Representatives of the 5 gene families were accurately identified (specificities and sensitivities of 100%) within 4.5 hours. This test may be helpful to differentiate carbapenem resistance mediated by carbapenemases from those involving other mechanisms.
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Authors
G. Cuzon, T. Naas, P. Bogaerts, Y. Glupczynski, P. Nordmann,