| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6116796 | Human Immunology | 2013 | 6 Pages |
Abstract
This large case-control and family based association study shows that HLA-Câ12/Bâ38, HLA-Bâ27 and HLA-Câ06/Bâ57 are haplotypes (alleles) robustly associated with PsA. However, since patients with PsA also have psoriasis it is difficult to determine whether the primary association is with arthritis or psoriasis.
Keywords
CASPKirSPASSOSSPJIAFDRPSAspondyloarthritisCASPARFBATsequence specific oligonucleotidenatural killerDNAPCAJuvenile idiopathic arthritispsoriatic arthritisFamily-based association testsequence specific primersHuman leukocyte antigenHLAAnkylosing spondylitisdeoxyribonucleic acidExpectation–MaximizationPrincipal component analysiscluster of differentiationWorld Health OrganizationLinkage disequilibriumMHCmajor histocompatibility complexGenome-wide association studyGWASfalse discovery rateodds ratiopolymerase chain reactionPCRSingle nucleotide polymorphismsSNPWHOKiller-cell immunoglobulin-like receptors
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Authors
Vinod Chandran, Shelley B. Bull, Fawnda J. Pellett, Renise Ayearst, Proton Rahman, Dafna D. Gladman,