Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6117309 | Immunology Letters | 2013 | 9 Pages |
Abstract
⺠We examined development of TCRαβ CD8αα IELs in RhoH knockout (KO) mice. ⺠RhoH KO mice had normal number of TCRαβ CD8αα T cells in the intestine. ⺠Activation of TCRαβ CD8αα IELs was impaired in RhoH KO mice. ⺠We propose a distinct molecular requirement for RhoH among agonist selected T cells.
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Authors
Hiroyo Oda, Norimasa Tamehiro, Michael S. Patrick, Kunihiro Hayakawa, Harumi Suzuki,