Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6117312 | Immunology Letters | 2013 | 8 Pages |
Abstract
⺠Conventional PKCα and PKCβ isotypes have overlapping functions in T cell activation signalling. ⺠PKCα and PKCβ cooperate functionally to mediate IL-2 gene expression.
Keywords
NFATPKCβnuclear factor of κBinhibitor of NFκBPDBuNP-40PKDAP1PKCαIFNγIKKPKCIκBFACSCPMTCrERKqRT-PCRIL-2IκB kinaseNFκBElectrophoretic mobility shift assayInterleukin-2Western blot analysisEMSA یا electrophoretic mobility shift assay counts per minutephorbol 12,13-dibutyrateT cell activationfluorescence activated cell sorterquantitative real time polymerase chain reactionCytokine responseactivator protein 1protein kinase DProtein kinase Cextracellular regulated kinaseInterferon gammaT cell receptor
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Authors
Lutz-Nicoladoni Christina, Thuille Nikolaus, Wachowicz Katarzyna, Gruber Thomas, Leitges Michael, Baier Gottfried,