| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6117314 | Immunology Letters | 2013 | 4 Pages |
Abstract
⺠Increasing antigen dose can overcome the reported deficiency of CCR9â/â mice to develop normal immune tolerance to oral antigens. ⺠The CCR9 antagonist, CCX507, does not affect the ability of mice to develop normal immune tolerance to oral antigens. ⺠The results obtained in CCR9â/â mice do not necessarily predict the results of pharmacological inhibition of CCR9.
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Authors
Matthew J. Walters, Karen Ebsworth, Timothy J. Sullivan, Penglie Zhang, Jay P. Powers, Juan C. Jaen, Thomas J. Schall,