| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6117317 | Immunology Letters | 2013 | 7 Pages |
Abstract
⺠Suppressive ODNs significantly reduce liver necroinflammatory injury and serum IFN-γ level in Con A-induced hepatitis model. ⺠The mortality of suppressive ODNs-treated mice is reduced post Con A challenge. ⺠Suppressive ODNs inhibit the development of Con A-induced hepatitis through down-regulation of STAT1/4 and T-bet pathways. ⺠Suppressive ODNs may be of use in the treatment of autoimmune or viral hepatitis in humans.
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Authors
Ning Li, Yue-Hui Liu, Sha-Ling Li, Chun-Yan Fu, Rong-Rong Zhou, Yan Huang, Xue-Gong Fan,