| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6117352 | Immunology Letters | 2011 | 7 Pages |
Abstract
⺠Complement and kinin systems play a role in hereditary and acquired angioedema. ⺠C1-inhibitor controls activation of both kinin and complement systems. ⺠Bradykinin contributes to angioedema attacks interacting with B2 receptors. ⺠Interaction of high molecular weight kininogen with gC1qR induces bradykinin release. ⺠B1 and gC1q receptors represent novel therapeutic targets for angioedema attacks.
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Authors
Fleur Bossi, Ellinor I. Peerschke, Berhane Ghebrehiwet, Francesco Tedesco,