Article ID Journal Published Year Pages File Type
6117357 Immunology Letters 2011 8 Pages PDF
Abstract
► Poly(γ-glutamic acid) (γ-PGA) nanoparticles (NPs) have great potential as an adjuvant and carrier of various antigens in vaccines. ► Antigen-carrying NPs were taken up much more efficiently by dendritic cells than antigen alone or aluminum-associated one. ► Antigen-carrying γ-PGA NPs proved to be a more potent inducer of antigen-specific cellular immune responses than other aluminum adjuvants.
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Related Topics
Life Sciences Immunology and Microbiology Immunology
Preview
Comparative activity of biodegradable nanoparticles with aluminum adjuvants: Antigen uptake by dendritic cells and induction of immune response in mice
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