| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6117361 | Immunology Letters | 2011 | 7 Pages |
Abstract
- We used human PBMC-derived and mice marrow-derived dendritic cells as models.
- We demonstrated that recombinant human calcineurin subunit B (CnB) induced phenotypic maturation of human PBMC-DCs and increased the secretion of cytokines.
- In vivo experiments, we used murine models to examine the adjuvant effect of CnB on recombinant pneumolysin antigen (PN) specific immune responses.
- It effectively promoted mixed Th1/Th2 type immune response.
Keywords
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Authors
Jing Li, MinLing Hu, JunXia Guo, ZhenYi Su, Qun Wei,