| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6117384 | Immunology Letters | 2012 | 7 Pages |
Abstract
⺠G-CSF-mobilized myeloid cells (gMCs) in donor grafts of peripheral blood stem cell transplantation (PBSCT) constitutively express TLR2. ⺠Ligation of TLR2 with a specific agonist dramatically enhanced cytokine production and survival of gMCs. ⺠TLR2-stimulated gMCs significantly promoted myeloid differentiation of donor hematopoietic stem cells (HSCs), resulting in accelerated engraftment after allogeneic transplantation.
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Authors
Won-Sik Lee, Young-Don Joo, Kyeong-Hee Oh, Hae-Jeong Won, Sun-Mi Lee, Moon-Young Choi, Gi-Ho Han, Sae-Gwang Park, Il-Whan Choi, Inhack Choi, Su-Kil Seo,