Article ID Journal Published Year Pages File Type
6117420 Immunology Letters 2011 6 Pages PDF
Abstract
► IL-33 seems to promote Th2-associated inflammations and allergic diseases. ► Stimulating factors for IL-33 production are less well characterized. ► We examined the effect of PGE2 on IL-33 production by dendritic cells. ► PGE2 dramatically enhanced IL-33 production by dendritic cells upon LPS stimulation. ► PGE2 may promote Th2-mediated inflammations through the enhancement of IL-33 production.
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