| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6117423 | Immunology Letters | 2011 | 9 Pages |
Abstract
⺠We investigated the antitumor activity and its immunological mechanisms of SEP in H22-bearing mice. ⺠SEP effectively inhibited hepatocellular carcinoma via enhancement of splenocyte proliferation, T cell numbers and activity. ⺠SEP also elevated IL-2 and TNF-α secretion as well as IgA, IgM and IgG levels in the serum. ⺠Erk phosphorylation and NFAT promoter activated by SEP promoted the transcription and expression of downstream gene IL-2.
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Authors
Mengyu Wang, Hui Wang, Ying Tang, Di Kang, Yu Gao, Mengyun Ke, Jie Dou, Tao Xi, Changlin Zhou,