Article ID Journal Published Year Pages File Type
6117434 Immunology Letters 2011 5 Pages PDF
Abstract
► We study GSTT1 donor/recipient mismatch in hematopoietic stem cell transplant. ► Null genotype parous female donors sometimes carry memory B cells against GSTT1. ► After the transplant, anti-GSTT1 ab-production against recipient's ag is triggered. ► GSTT1 mismatch and GSTT1 abs are risk factors for hepatic graft-versus-host-disease. ► GSTT1 is a new minor histocompatibility antigen involved in GVHD.
Related Topics
Life Sciences Immunology and Microbiology Immunology
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