Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6117495 | Immunology Letters | 2010 | 4 Pages |
Abstract
We previously described a patient with a history of frequent life-threatening pneumonias, infections with bacterial pathogens, interleukin 1 receptor-associated kinase 4 deficiency, and failure to maintain antibody titers to polysaccharide antigens or to a neoantigen bacteriophage. In the present study, we show that the patient's peripheral blood mononuclear cells have a profound deficiency of invariant natural killer T cells.
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Authors
Soichi Haraguchi, Noorbibi K. Day, Nutthapong Tangsinmankong, John W. Sleasman,