| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6118419 | International Journal of Antimicrobial Agents | 2011 | 7 Pages |
Abstract
Several compounds isolated from the plant Carpobrotus edulis were evaluated for their activity against multidrug-resistant (MDR) bacteria and their efflux pump systems. Amongst the compounds isolated, six compounds were tested, namely uvaol, β-amyrin, oleanolic acid, catechin, epicatechin and monogalactosyldiacylglycerol. Oleanolic acid presented high antibacterial activity against a large number of bacterial strains. The triterpene uvaol was the most active compound for modulation of efflux activity by MDR Gram-positive strains.
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Authors
A. Martins, A. Vasas, M. Viveiros, J. Molnár, J. Hohmann, L. Amaral,