Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6118423 | International Journal of Antimicrobial Agents | 2011 | 5 Pages |
Abstract
In this study, 183 Salmonella enterica isolates were characterised for integrons and virulence genes. Among the isolates, 46% were positive for intI1, but no isolates carried intI2 or intI3. Eighteen class 1 integrons (21%) contained resistance gene cassettes (i.e. dfrA1-orfC, dfrA12-aadA2, blaPSE-1 and aadA2) and five class 1 integrons with the dfrA12-aadA2 array were conjugally transferable. Two Salmonella pork isolates of serotypes Albany and Kedougou possessed Salmonella genomic island 1 variants SGI1-G and SGI1-F, respectively. Four class 1 integrons contained an atypical 3â²-CS linked to the qacH-sul3 domain, and three were not a sul type. Two novel GyrA mutations (Pro-45âSer and Met-48âIle) and three novel ParC mutations (Ser-5âArg, Thr-31âMet and Leu-77âArg) were identified in ciprofloxacin-resistant isolates. At least 90% of the Salmonella isolates contained pagC, prgH, sitC, sipB or spaN, whereas all isolates harboured invA, msgA, spiA and tolC.
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Authors
Wechsiri Wannaprasat, Pawin Padungtod, Rungtip Chuanchuen,