Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6119254 | Journal of Autoimmunity | 2015 | 13 Pages |
Abstract
Our results identify core mechanisms dictating human tTreg development, with IL-2 and IL-15 defining specific niches required for tTreg lineage stabilization and differentiation, with implications for their therapeutic targeting in autoimmune conditions.
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Authors
Iris Caramalho, Vânia Nunes-Silva, Ana R. Pires, Catarina Mota, Ana I. Pinto, Helena Nunes-Cabaço, Russell B. Foxall, Ana E. Sousa,