Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6119347 | Journal of Autoimmunity | 2012 | 9 Pages |
Abstract
⺠Responses following environmental exposures in animals depend on genetic background. ⺠Animal models have enough features of human disease to provide useful information. ⺠Strengths of animal models: genetic homogeneity and control of experimental design. ⺠Animal models provide strong data linking certain exposures to autoimmune disease. ⺠Other exposures likely impact autoimmunity, but require confirmation.
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Authors
Dori Germolec, Dwight H. Kono, Jean C. Pfau, K. Michael Pollard,