Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6119348 | Journal of Autoimmunity | 2012 | 10 Pages |
Abstract
⺠Th17 cells are linked to tissue-destructive inflammation in periodontitis. ⺠Th17 driving cytokines are abundant in tissues of periodontitis. âºÂ The periodontal pathogen P. gingivalis may orchestrate induction of Th17 pathways. ⺠P. gingivalis drives production of Th17 not Th1 cytokines. ⺠P. gingivalis selectively degrades cytokine mediators favoring a Th17 milieu.
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Authors
Niki M. Moutsopoulos, Heather M. Kling, Nikola Angelov, Wenwen Jin, Robert J. Palmer, Salvador Nares, Manuel Osorio, Sharon M. Wahl,